Uncontrolled blood pressure and its risk factors among hypertensive patients, Marrakech, Morocco.

Hypertension is a public health problem. Failure to control blood pressure figures is responsible for morbidity and premature mortality. This study aims to describe the characteristics of hypertensive patients followed at primary health care centers in Marrakech. Between May 2021 and December 2022, a cross-sectional study of 922 hypertension patients attending primary health care centers in Marrakech was done. To gather socio-demographic, behavioral, and clinical data, as well as hypertension treatment features and the care-patient-physician triad, a face-to-face questionnaire was employed. To identify risk factors associated with uncontrolled blood pressure, multivariate logistic regression was used. Uncontrolled blood pressure was found in 73.5% of people. The patients' average age was 63.4 ± 9.4 years (mean ± standard deviation), and 524 (77.3%) were women. Tobacco consumption (Adjusted Odd Ratio of 4.34; 95% CI [1.58-11.9]); lack of self-monitoring of hypertension (AOR of 1.69; 95% CI [1.14-2.52]); a family history of hypertension (AOR of 1.58; 95% CI [1.12-2.22]); overweight or obesity (AOR of 1.73; 95% CI [1.15-2.58]); and nonadherence to antihypertensive medication (AOR of 1.58; 95% CI [1.05-2.38]) were identified as risk factors for uncontrolled blood pressure. In hypertensive individuals, the percentage of uncontrolled blood pressure is considerable. It is essential to provide therapeutic education classes for hypertension patients in order to strengthen their power and autonomy in managing their hypertension.

[Influence of white blood cells count on parasite density in Malaria in children aged 6 to 59 months in Benin]. / Influence de la numération leucocytaire sur la densité parasitaire dans le paludisme simple chez les enfants de 6 à 59 mois au Bénin.

Background: For many years, the treatment of malaria was based on clinical presumptive diagnosis, making its differential diagnosis with other causes of hyperthermia difficult. This drug pressure has led to the emergence of Plasmodium strains resistant to the most commonly used antimalarial drugs. This is why in 2004, the health authorities decided to revise the policy of malaria management by adopting a new strategy based on the rational use of artemisininbased combination therapies after the biological confirmation of suspected malaria cases. The biological diagnosis is an essential part of malaria management. The gold standard technique for diagnosis is the thick drop combined with the calculation of parasite density (PD), which is determined on the basis of the number of parasites counted in a microscopic field against a proposed standard number of leukocytes. The number of leukocytes used to calculate the parasite density should ideally be the actual number of leukocytes in the patient per cubic millimetre of blood. However, in the absence of the availability of a blood count at the time of the thick drop, an average number of 8 000 leukocytes/mm3 was used by the World Health Organisation (WHO) to estimate the parasite density. Nonetheless, in Benin the average number of leukocytes adopted by the National Malaria Control Programme (PNLP) is 6 000/mm3. The aim of our study was to determine the impact of the leukocyte count on the calculation of the parasite density in cases of uncomplicated malaria. Method: The study was a cross-sectional study with an analytical aim and took place in 2 hospitals in Benin, the Klouékanmey zone hospital in the south of Benin and the Djougou health centre in the north. It involved a population of 476 children aged between 6 and 59 months who were seen in consultation and in whom the clinical diagnosis of simple Plasmodium falciparum malaria was suspected. Children aged between 6 and 59 months, weighing at least 5 kg, with an axillary temperature ≥ 37.5°C at the time of consultation or a history of fever in the last 24 hours or other symptoms pointing to the diagnosis of malaria were included. Infestation was mono-specific for Plasmodium falciparum. Informed consent was required from the child's parents or guardian. The criteria for non-inclusion in our study were the presence of at least one sign of malaria severity, signs of severe malnutrition or a febrile state related to underlying infectious diseases other than malaria. Thick blood count and haemogram were systematically performed in all included children. Parasite density was calculated according to 3 methods, first using a weighted leukocyte count of 6 000/mm3 recommended by the Benin National Malaria Control Programme (PNLP), then a leukocyte count of 8 000/mm3 recommended by the World Health Organisation and finally the patient's actual leukocyte count obtained from the blood count. It should be noted that these different samples were respectively taken on the day of inclusion in compliance with the conditions of the pre-analytical phase in force in our medical biology laboratory. Results: At the end of our study, 313 children, i.e. 65.76% of our study population had a positive white blood cell count with a positivity rate of 62.14% in Djougou, i.e. 174 children, and 70.9% in Klouékanmey, i.e. 139 children. The average leukocyte count in these children was 11,580/mm3. Among them, 205 children had an abnormal white blood cell count, i.e. 17 cases of leukopenia (5.43%) and 188 cases of hyperleukocytosis (60.06%). Using successively the average number of 6 000 leukocytes/mm3 proposed by the Benin PNLP and that of 8 000 leukocytes/mm3 proposed by the WHO, the average parasite densities were respectively 47,943 and 63,936 trophozoïtes/µl against 92,290 trophozoïtes/µl when the real number of leukocytes of the patients was used for the calculation of the PD. By using an average of 6 000 leukocytes/mm3 for PD calculation, 60% of the calculated PDs were underestimated and 6% were overestimated. Using an average of 8 000 leukocytes/mm3 resulted in 49% of PD being underestimated and 15% being overestimated. The difference between the three calculation methods was considered statistically significant (p value <0.05). Conclusion: The use of 6 000 or 8 000 coefficients for the estimation of parasitaemia could lead to a significant underestimation of the parasite load.

[Red blood cell alloimmunization among polytransfused patients in the National Hospital and University Center of Cotonou: about 51 cases]. / Allo-immunisation anti-érythrocytaire chez les polytransfusés au Centre National Hospitalier Universitaire de Cotonou: à propos de 51 cas.

Blood transfusion is a medical procedure used to treat patients with labile blood product. Each transfusion of globular concentrate exposes recipients to the risk of red blood cell alloimmunization. The test for red cell antibodies (RCA) ensures the immunohaematological safety of transfused patients. In Benin, this test is not performed in a systematic way or included either in the pre-transfusion or in the post-transfusion tests. The purpose of this study is to determine the presence of red cell antibodies among polytransfused patients. RCA was performed using indirect antiglobulin test on gel-filtration in 51 polytransfused patients including 26 selected in the Department of Hematology and 25 in the Department of Nephrology at the National Hospital and University Center of Cotonou. After phenotyping alloimmunized patients, tests for detecting signs of hemolysis were performed. Clinical data as well as those on transfusion were collected from transfusion registries and medical records. The prevalence of alloimmunization in our study population was 13.73%. The antibodies identified had the following characteristics: association of anti-RH1 and anti-RH3, anti LE1, association of anti-RH3 and anti-FY1. Alloantibodies were more frequent in patients who had received more than 15 packed red blood cells. Laboratory tests showed signs of hemolysis in one alloimmunized patient. There was no correlation between age, sex, clinical diagnosis and the occurrence of red blood cell alloimmunization. The test for red cell antibodies should be systematically performed in polytransfused patients in order to ensure better transfusion recipient safety in Benin.

From benchmarking to best practices: Lessons from the laboratory quality improvement programme at the military teaching hospital in Cotonou, Benin.

BACKGROUND: In 2015, the Army Teaching Hospital-University Teaching Hospital (HIA-CHU [Hôpital D'instruction des Armées de Cotonou Centre Hospitalier et Universitaire]) laboratory in Benin launched a quality improvement programme in alignment with the World Health Organization Regional Office for Africa's Stepwise Laboratory Improvement Process Towards Accreditation (SLIPTA). Among the sub-Saharan African laboratories that have used SLIPTA, few have been francophone countries, and fewer have belonged to a military health system. The purpose of this article was to outline the strategy, implementation, outcomes and military-specific challenges of the HIA-CHU laboratory quality improvement programme from 2015 to 2018. INTERVENTION: The strategy for the quality improvement programme included: external baseline SLIPTA evaluation, creation of work plan based on SLIPTA results, execution of improvement projects guided by work plan, assurance of accountability via regular meetings, training of personnel to improve personnel competencies, development of external stakeholder relationships for sustainability and external follow-up post-SLIPTA evaluation. LESSONS LEARNT: Over a period of 3 years, the HIA-CHU laboratory improved its SLIPTA score by 29% through a quality improvement process guided by work plan implementation, quality management system documentation, introduction of new proficiency testing and internal quality control programmes, and enhancement of personnel competencies in technical and quality management through training. RECOMMENDATIONS: The programme has yielded achievements, but consistent improvement efforts are necessary to address programme challenges and ensure continual increases in SLIPTA scores. Despite successes, military-specific challenges such as the high mobility of personnel have hindered programme progress. The authors recommend that further implementation research data be shared from programmes using SLIPTA in under-represented settings such as military health systems.

Prevalence of hemoglobin abnormalities in an apparently healthy population in Benin

ABSTRACT Background: Sickle cell disease is the most common monogenic disorder in humans and is a major public health concern in sub-Saharan Africa. In Benin, the prevalence of sickle cell disease is estimated to be 4.8%. Our study aimed to describe the prevalence of hemoglobin abnormalities in an apparently healthy Benin population. Methods: One thousand four hundred and eighty-three men and women, apparently in good health after medical screening, were tested for hemoglobin abnormalities by hemoglobin electrophoresis and the Emmel test. Subjects who were found to have homozygous or double heterozygous hemoglobin abnormalities, were re-sampled and a confirmation hemogram and hemoglobin electrophoresis test by capillary electrophoresis was performed. Results: Our study population was predominantly male (97.7%) with an average age of 21.3 years. 1390 subjects reported that they did not know their hemoglobin electrophoresis status. Hemoglobin electrophoresis profiles found were as follows: 1077 (72.6%) AA (normal), 238 (16.1%) AS, 161 (10.9%) AC, 3 (0.2%) SC, 4 (0.2%) CC and 0 (0%) SS. The 406 subjects with abnormal hemoglobin had balanced somatic growth, with general physical examination results showing no abnormalities. In the seven subjects with major sickle cell syndrome or hemoglobinosis (SC and CC), their values of various hemogram parameters were normal apart from the discreet presence of microcytic anemia. Conclusion: Our study highlights the need for increased routine testing of hemoglobin abnormalities and newborn screening for sickle cell disease in order to enhance early disease detection, prevention and comprehensive care.

Prevalence of hemoglobin abnormalities in an apparently healthy population in Benin.

BACKGROUND: Sickle cell disease is the most common monogenic disorder in humans and is a major public health concern in sub-Saharan Africa. In Benin, the prevalence of sickle cell disease is estimated to be 4.8%. Our study aimed to describe the prevalence of hemoglobin abnormalities in an apparently healthy Benin population. METHODS: One thousand four hundred and eighty-three men and women, apparently in good health after medical screening, were tested for hemoglobin abnormalities by hemoglobin electrophoresis and the Emmel test. Subjects who were found to have homozygous or double heterozygous hemoglobin abnormalities, were re-sampled and a confirmation hemogram and hemoglobin electrophoresis test by capillary electrophoresis was performed. RESULTS: Our study population was predominantly male (97.7%) with an average age of 21.3 years. 1390 subjects reported that they did not know their hemoglobin electrophoresis status. Hemoglobin electrophoresis profiles found were as follows: 1077 (72.6%) AA (normal), 238 (16.1%) AS, 161 (10.9%) AC, 3 (0.2%) SC, 4 (0.2%) CC and 0 (0%) SS. The 406 subjects with abnormal hemoglobin had balanced somatic growth, with general physical examination results showing no abnormalities. In the seven subjects with major sickle cell syndrome or hemoglobinosis (SC and CC), their values of various hemogram parameters were normal apart from the discreet presence of microcytic anemia. CONCLUSION: Our study highlights the need for increased routine testing of hemoglobin abnormalities and newborn screening for sickle cell disease in order to enhance early disease detection, prevention and comprehensive care.

Anomalies immuno-hématologiques et maladies auto-immunes au Centre National Hospitalier Universitaire Hubert Koutoukou Maga (CNHU/HKM) de Cotonou

Introduction : Les maladies auto-immunes (MAI) sont associées à des manifestations immuno-hématologiques de gravité variable. Objectif : Décrire les anomalies immuno-hématologiques retrouvées chez les patients atteints de MAI au CNHU-HKM de Cotonou. Matériels et méthode : Etude prospective, transversale à visée descriptive et analytique menée de novembre 2017 à février 2018 dans les services de Médecine Interne, de Rhumatologie et des Mala-dies du Sang du CNHU-HKM. Le laboratoire d'Hématologie Biologique et celui de Biochimie du même centre ont servi pour la réalisation des différentes explorations biologiques. Résultats : Quarante-quatre patients connus et suivis pour MAI ont été inclus. Parmi eux, 90,9% étaient des femmes. La moyenne d'âge était de 39,7 ans. La polyarthrite rhumatoïde (PR) et le lupus érythémateux systématique (LES) étaient les MAI les plus présentes avec des fréquences respectives de 59,1% et 29,5%. Au plan des analyses biologiques, 24 malades présentaient au moins une anoma-lie de l'hémogramme. Les principales anomalies quantitatives retrouvées étaient l'anémie et la lym-phopénie avec des fréquences respectives de 35,1% et 32,4%. Des anomalies qualitatives touchaient les hématies et les plaquettes. Sept patients sur les 44 possédaient des auto-anticorps anti-érythrocytaires. La présence de ces auto-anticorps était associée à des anomalies de l'hémogramme.Conclusion : Notre étude met en exergue la fréquence élevée des anomalies hématologiques chez les patients atteints de MAI et le rôle important du laboratoire d'hématologie dans leur prise en charge. La prise en charge de ces patients requiert une parfaite collaboration interdisciplinaire

Performance des médécins dans la démarche diagnostique des anémies dans la ville de Cotonou: évolution de 2011 à 2016

Introduction : L'anémie est un problème de santé publique. Pour une prise en charge efficace, une démarche diagnostique méthodique et rigoureuse doit être observée. Objectif : Evaluer l'évolution de la performance théorique et pratique des médecins en matière de diagnostic des anémies entre 2011 et 2016. Méthodologie : Dans la continuité d'une étude réalisée en 2011, 133 médecins ont été évalué sur leurs performances théoriques et pratiques à mener la démarche diagnostique des anémies. Les con-naissances théoriques ont été évaluées par un questionnaire. La performance pratique a été évaluée à l'aide de 60 dossiers de patients traités pour une anémie non drépanocytaire dans les formationssanitaires retenues. Les différents scores obtenus ont été comparés à ceux de 2011. Résultats : L'analyse globale des résultats montre que 48,1% des médecins enquêtés ont eu une performance insuffisante contre 87,9% en 2011 ; une performance acceptable de 50,4% contre 12,1% en 2011 pour la démarche diagnostique théorique. En ce qui concerne la performance diagnostique pratique, 53,3% des médecins avaient une performance insuffisante contre 74% en 2011 et une per-formance acceptable de 46,7% contre 26% en 2011. Les scores enregistrés en 2016 sont meilleurs à ceux retrouvés en 2011 (p=0,000%) Conclusion : Outre le renforcement de l'enseignement des anémies durant les formations médicales,une politique de formation continue est nécessaire pour remédier aux insuffisances constatées

L'expérience en cytologie hématologique au Bénin

Introduction : La maîtrise de la cytologie hématologique reste indispensable malgré l'avènement des automates. Objectif : Faire le point de la pratique de la cytologie hématologique au Bénin. Matériels et méthode : Etude transversale à visée descriptive et analytique comportant un volet ré-trospectif et un volet prospectif. Seize formations sanitaires tirées au hasard et réparties sur l'ensemble des 34 zones sanitaires que compte le pays avaient été incluses en tenant compte des différents niveaux de la pyramide sanitaire. Les données enregistrées ont été saisies avec Excel et analysées grâce au logiciel Epi info version 7.2. Résultats : Six hôpitaux sur 16 avaient un laboratoire d'Hématologie et seul le laboratoire d'Hématologie du Centre National Hospitalier Universitaire-HKM disposait de personnels spécialistes. Le nombre moyen de technicien était de 5 par centre et 60,4% d'entre eux étaient de niveau A. Le nombre moyen d'hémogrammes réalisés par mois était de 3000 pour le CNHU, 603 pour les Hôpitaux de zone et 549 pour les Centres Hospitaliers départementaux. L'étude du frottis sanguin était de réalisation systématique dans seulement 6 centres. Aucune autre activité de cytologie hématologique en dehors de l'hémogramme n'était réalisée sauf au CNHU-HKM et à l'Hôpital de zone de Tanguiéta qui réalisaient des myélogrammes et des adénogrammes. Ces deux derniers centres disposaient également d'un dispositif de télé-hémato-cytologie. Conclusion : Notre étude révèle des insuffisances en cytologie hématologique. Les solutions propo-sées passent par le recrutement et la formation de personnels qualifiés, l'équipement et l'approvisionnement des laboratoires

[Emergency treatment of sickle cell diseases in the Blood Diseases Department at the Koutoukou Maga National Teaching Hospital, Cotonou, Benin]. / Urgences drépanocytaires au Service des Maladies du Sang du Centre National Hospitalier Universitaire-Hubert Koutoukou Maga de Cotonou, Benin.

INTRODUCTION: Evolution of sickle cell disease is marked by the occurrence of acute complications, some of which are real emergencies that can give rise to life-threatening or functional cosequences. This study aims to evaluate the frequency and the evolution of emergency treatment of sickle cell disease in the Blood Diseases Department at the Koutoukou Maga National Teaching Hospital, Cotonou. METHODS: We conducted a retrospective and descriptive study of all patients hospitalized for emergency treatment of sickle cell disease from January 2014 to December 2015. We excluded patients hospitalized for chronic sickle cell disease complications. RESULTS: Out of 813 hospitalizations, two hundred and four (204) emergency treatments of sickle cell disease were registered (prevalence 25%). The average age of our patients was 24.2 years. The most represented age group was 20-30 years (45.6%). Male sex predominated (60.8%). Pupils/students was the most represented group (55.9%). Acute pain was the primary reason for hospitalization to 63.7%. Normal homozygous individuals (SS) were mostly represented (72.1%). Osteoarticular vaso-occlusive complications predominated (70.1%). Documented infectious complications were dominated by malaria (27.5%). Decompensated anemia accounted for 30.4%. Therapeutic approach was based on hydration (85.3%). The average length of stay in hospital was 5.4 days. Outcome was favorable in 96,5% of cases. Mortality accounted for 2.5%. CONCLUSION: Emergency treatments of sickle cell disease are frequent. Early diagnosis as well as early and effective management are necessary. Ongoing training programs in emergency treatments of sickle cell disease are necessary to reduce mortality.

[Difficulties in interpreting the monoclonal gammopathy of chance discovery: transitional gammopathy case in a significant inflammatory syndrome]. / Difficultés d'interprétation des gammapathies monoclonales de découverte fortuite : cas d'une gammapathie transitoire au cours d'un syndrome inflammatoire important.

The discovery of a monoclonal immunoglobulin is usually witnessed a malignant lymphoproliferative disease, but sometimes it is a transient event during viral, bacterial or fungal infections and during an inflammatory syndrome. Achieving electrophoresis performed in an elderly patient aged 55 with anemia to 63 g/L hemoglobin showed a consistent profile with intense inflammatory syndrome and chronic atypical with elevated C-reactive protein (CRP) greater than 300 mg/L (normal values: 0-8 mg/L) associated with the presence of two thin appearance monoclonal migrating bands in gamma position. Achieving immunofixation showed IgM kappa monoclonal confirmed by using betamercaptoethanol (BME). Radiological findings, hematological, revealed nothing. The recovery of blood away from the inflammation on another sample report presented a CRP at 5 mg/L and a subnormal profile electrophoresis and immunofixation revealed nothing. The comparison of the results of biochemical investigations, haematological and clinical and radiological control of the electrophoretic profile of a remote inflammatory syndrome to exclude cases of transient gammopathies.

[Utility of hCG dosage in the management of gestational trophoblastic diseases]. / Intérêt du dosage de l'hormone chorionique gonadotrope dans les maladies trophoblastiques gestationnelles.

Measurement of hCG remains today central for diagnosis, treatment and follow-up of gestational trophoblastic diseases (GTD). In order to evaluate this contribution, we conducted a prospective cohort study in the Service of high-risk pregnancy of Rabat Maternity Les Orangers and the Laboratory of Rabat Military Teaching Hospital Mohammed V over a period of eighteen months. 35 patients were included. The hCG assay was determined by electrochemiluminescence. The general frequency of the GTD is of 0.33/100 childbirth. The average age of our patients was 30.5 years. 26 patients had hCG level abnormal and higher than 200 000 UI/mL when diagnosed with GTD; 34 patients had simple endo-uterine aspiration and 1 a chemotherapy. Among 34 patients, 25 (73.5%) had a favourable evolution characterized by normal hCG level within 3 to 13 weeks and complete remission. Serum hCG remained stable and negative in all these patients with a follow-up of 18 months. 9 patients had unfavourable evolution characterized by reaxent after negativation or stagnation of hCG levels. A rigorous monitoring of hCG levels during treatment and follow-up is essential to improve forecast of these diseases.

[Prevalence of Acinetobacter baumannii and Pseudomonas aeruginosa isolates resistant to imipenem by production of metallo-ß-lactamases in Rabat Military Teaching Hospital Mohammed V]. / Résistance à l'imipénème par production de métallo-ß-lactamases par Acinetobacter baumannii et Pseudomonas aeruginosa à l'Hôpital militaire d'instruction Mohammed V de Rabat.

We studied the production of metallo-ß-lactamases (MBL) in Acinetobacter baumannii and Pseudomonas aeruginosa strains resistant to imipenem at the Rabat Mohammed V military teaching hospital, according to Yong et al.'s method, using a sterilized solution of EDTA 0.5 M pH 8. One hundred and five bacterial strains (48 A. baumannii and 57 P. aeruginosa) were identified. 45 (42.9%) with 34 A. baumannii and 11 P. aeruginosa were resistant to imipenem. The prevalence of MBL producing strains was 22.2% (10/45). The existence of this isolates resistant to imipenem by producing metallo-ß-lactamases is an emerging public health problem. It is necessary to implemente infection control programs to avoid spreading of multidrug resistant bacteria.

Burn unit: colonization of burn wounds and local environment.

BACKGROUND: We present the results of a comparative prospective study of the resistance profile of strains isolated from pathological material of patients hospitalized in the burn unit of the military hospital in Rabat and from their environment over a period of one and a half years (July 2009-February 2011). METHODS: The study concerned 125 pathological products from patients (40 men, 20 women; mean age 38±14.8 years; range 2 to 80 years) hospitalized with burns. This allowed the isolation of 86 non-redundant bacterial strains during the first period and 50 during the second. RESULTS: The dominant species were Acinetobacter baumannii (15.6%), followed by Pseudomonas aeruginosa (13.8%) and Staphylococcus aureus (11%). During the second period, we noted the abundance of A. baumannii (15.5%), followed by P. aeruginosa (11.3%) and Klebsiella pneumoniae (8.5%). Of the 104 environmental samples of burn patients, 139 microorganisms were isolated. Coagulase-negative staphylococcus was the most abundant strain in the two study periods (69.2% and 64.6%). CONCLUSION: All species showed an almost identical sensitivity to the various antibiotics tested.

[A Corynebacterium striatum endocarditis on a carrier of pacemaker]. / Endocardite à Corynebacterium striatum chez un porteur de stimulateur cardiaque.

We report a new case of a Corynebacterium striatum endocarditis on a carrier of a pacemaker. Corynebacterium striatum was isolated from blood culture, the pulse generator and the pacing lead. A literature review of Corynebacterium striatum endocarditis on a carrier of pacemaker was conducted.

[Bacterial epidemiology in the burns unit at military teaching hospital Mohamed V of Rabat]. / Épidémiologie bactérienne à l'unité des brûlés de l'Hôpital militaire d'instruction de Rabat.

We aimed to establish the ecology of the Burns Unit of the Military Teaching Hospital Mohammed V of Rabat. We present results of a retrospective study of four years (March 2006-June 2010) on all micro-organisms isolated from patient samples. During the study period, we analyzed 307 samples corresponding to isolate bacterial strains from 288 non-redundant and 5 yeasts among which 4 corresponded to Candida albicans. The bacteriological profile of the isolated stumps showed a change between 2006 and 2010. Staphylococcus aureus in 2007 and 2008 (52.3%, 33.9%) was in 3rd position in 2010 (10.5%). Acinetobacter baumannii found in 3rd position or below (3.7%, 11.6%, 15.3%), between 2006 and 2008, reached the summit in 2009 and 2010 (22.6% and 23.7%). Pseudomonas aeruginosa, strain dominant in 2006 (33.3%) maintained its second position in 2007, 2008 and 2010 (19.8%, 18.6%, 18.4%) while it was third in 2009 (14.3%). Study of the resistance in antibiotics of the main isolated bacteria showed a stability of the profile of resistance. In conclusion, an epidemiological surveillance of bacteria is necessary, in the burns unit and in the hospital, to guide better the probability antibiotic treatment.

[Antibacterial activity of antiseptics used at Military Teaching Hospital Mohamed V of Rabat]. / Activité antibactérienne des antiseptiques utilisés à l'Hôpital militaire d'instruction Mohamed V de Rabat.

Antiseptics have a major role against the infections and their prevention. The good management of antiseptics allows the reduction of antibiotics use and thus the emergence of resistant bacterial strains. The evaluation of the antibacterial activity of three antiseptics (povidone iodine [PVPI], iodized alcohol and alcohol 70 degrees) used at HMIMV and taken from pharmacy was based on AFNOR method NF T 72-150. The analysis of their chemical properties were done by standardized methods (manganimetry, Bunsen's method, test to determine sodium thiosulfate levels [or sodium thiosulfate test] and Guy Lussac alcoholmeter). Our results were compared with those obtained in another two university hospitals of Rabat: Hospital of Speciality and Ibn Sina. The frequencies of resistant bacterial strains were respectively 4.6%, 30.7% and 15.4% to PVPI, alcohol iodized and alcohol 70 degrees . Our results have shown that the PVPI is the best antiseptic in our hospital.